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Martin Scorsese’s Leonardo DiCaprio starrer “Shutter Island” docked at the high end of pre-release projections with an estimated $40.2 million. The R-rated suspense thriller’s outsize bow gave the film’s director and topliner new personal bests.
The twelve estimated top producing motion pictures for the weekend, per data collected as of Sunday February 21, 2010 include:
| Rank | Title | Distributor | Weekend Gross | Cume | Locations |
| 1 | Shutter Island | Paramount | $40,200,000 | $40,200,000 | 2991 |
| 2 | Valentine’s Day | Warner Bros. | $17,160,000 | $87,422,086 | 3665 |
| 3 | Avatar | 20th Century Fox | $16,100,000 | $687,821,154 | 2581 |
| 4 | Percy Jackson & The Olympians: Lightning | 20th Century Fox | $15,300,000 | $58,760,392 | 3396 |
| 5 | The Wolfman | Universal | $9,846,265 | $50,314,890 | 3223 |
| 6 | Dear John | Sony | $7,300,000 | $65,971,213 | 3062 |
| 7 | Tooth Fairy | 20th Century Fox | $4,500,000 | $49,867,120 | 2523 |
| 8 | Crazy Heart | 20th Century Fox | $3,025,000 | $21,585,198 | 1089 |
| 9 | From Paris With Love | Lionsgate | $2,500,000 | $21,199,675 | 2311 |
| 10 | Edge Of Darkness | Warner Bros. | $2,210,000 | $40,313,911 | 2118 |
| 11 | The Book Of Eli | Warner Bros. | $1,845,000 | $90,732,086 | 1455 |
| 12 | When In Rome | Disney | $1,747,000 | $29,354,070 | 1627 |
