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Novocaine easily topped the slowest moviegoing weekend of 2025 so far at the domestic box office, as well as one of the worst in the post-COVID-19 era. The film came in with an $8.7 million launch to ice out Mickey 17, which fell to No. 2 in its second frame. However, the studio had hoped to do closer $10 million. Novocaine stars Jack Quaid as a new kind of action hero who is not so great at dishing it out, but boy, can he take it — thanks to his genetics, which make him feel no harm.
Mickey 17 finished the weekend with around $7.5 million, tumbling more than 60 percent from its opening weekend . Just behind it at number three was Steven Soderbergh‘s new movie Black Bag.
The top 12 movies of the weekend, as of Sunday, March 16, are as follows,
| # | Title | Distributor Name | Weekend Total | # of Locs | Loc Avg | Cume Total | % Change |
|---|---|---|---|---|---|---|---|
| 1 | Novocaine | Paramount | $8,700,000 | 3,365 | $2,585 | $8,700,000 | |
| 2 | Mickey 17 | Warner Bros. | $7,510,000 | 3,807 | $1,973 | $33,287,000 | -60.48% |
| 3 | Black Bag | Focus Features | $7,500,000 | 2,705 | $2,773 | $7,500,000 | |
| 4 | Captain America: Brave New World | Disney | $5,479,000 | 3,250 | $1,686 | $185,396,912 | -35% |
| 5 | Day the Earth Blew Up: A Looney Tunes Movie, The | Falling Forward Films | $3,170,000 | 2,827 | $1,121 | $3,170,000 | |
| 6 | Last Supper, The | Emick | $2,825,000 | 1,575 | $1,794 | $2,825,000 | |
| 7 | Paddington in Peru | Sony | $2,775,000 | 2,489 | $1,115 | $41,318,000 | -25% |
| 8 | Dog Man | Universal | $2,500,000 | 2,407 | $1,039 | $92,818,000 | -26% |
| 9 | Monkey, The | Neon Rated | $2,465,000 | 2,294 | $1,075 | $35,212,015 | -37.05% |
| 10 | Last Breath | Focus Features | $2,300,000 | 2,661 | $864 | $18,563,000 | -44% |
| 11 | Mufasa: The Lion King | Disney | $1,193,000 | 1,175 | $1,015 | $252,438,475 | -28% |
| 12 | Opus | A24 | $1,013,273 | 1,764 | $574 | $1,013,273 |
