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Marvel Studios’ summer-launching comics action film “Iron Man 2” easily opened atop domestic rankings with an estimated $133.6 million in weekend box office. Unlike many recent movies, Iron Man dominated the box office without relying on the more expensive ticket price that 3D features have relied on.
The twelve estimated top producing motion pictures for the weekend, per data collected as of Sunday, May 9, 2010 include:
| Rank | Title | Distributor | Weekend Gross | Cume | Locations | |
| 1 | Iron Man 2 | Paramount | $133,600,000 | $133,600,000 | 4380 | |
| 2 | A Nightmare On Elm Street | Warner Bros. | $9,170,000 | $48,530,171 | 3332 | |
| 3 | How To Train Your Dragon | Paramount | $6,760,000 | $201,093,493 | 3003 | |
| 4 | Date Night | 20th Century Fox | $5,300,000 | $80,854,468 | 2734 | |
| 5 | The Back-Up Plan | CBS Films | $4,345,000 | $4,345,000 | N/A | |
| 6 | Furry Vengeance | Summit Entertainment | $4,000,000 | $11,621,957 | 3002 | |
| 7 | Clash Of The Titans | Warner Bros. | $2,305,000 | $157,808,026 | 2157 | |
| 8 | Death At A Funeral | So | $2,100,000 | $38,323,181 | 1706 | |
| 9 | The Losers | Warner Bros. | $1,800,000 | $21,449,617 | 2450 | |
| 10 | Babies | Focus Features | $1,575,594 | $1,575,594 | 534 | |
| 11 | Oceans | Disney | $1,532,000 | $16,057,648 | 1232 | |
| 12 | Kick Ass | Lionsgate | $1,510,000 | $45,286,146 | 1759 | |
