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The 3D animated comedy Megamind from DreamWorks Animation and Paramount eased executives’ minds on both lots with an estimated $47.7 million weekend opening that comfortably topped the domestic box office.
The Top-12 grossing motion pictures for the weekend, per data collected as of Sunday, November 7, 2010, are as follows:
| Rank | Film Name | Distributor Name | Weekend Revenue | Cume Revenue | Locs | Loc Avg |
|---|---|---|---|---|---|---|
| 1 | Megamind | Paramount | 47,650,000 | 47,650,000 | 3,944 | 12,081 |
| 2 | Due Date | Warner Bros. | 33,500,000 | 33,500,000 | 3,355 | 9,985 |
| 3 | For Colored Girls | Lionsgate | 20,100,000 | 20,100,000 | 2,127 | 9,449 |
| 4 | Red | Summit Entertainment | 8,858,000 | 71,870,876 | 3,229 | 2,743 |
| 5 | Saw 3D | Lionsgate | 8,200,000 | 38,800,708 | 2,808 | 2,920 |
| 6 | Paranormal Activity 2 | Paramount | 7,298,000 | 77,223,122 | 3,168 | 2,303 |
| 7 | Jackass 3D | Paramount | 5,097,000 | 110,814,075 | 2,165 | 2,354 |
| 8 | Hereafter | Warner Bros. | 4,020,000 | 28,729,669 | 2,365 | 1,699 |
| 9 | Secretariat | Disney | 4,002,000 | 50,965,353 | 2,614 | 1,530 |
| 10 | Social Network, The | Sony | 3,600,000 | 85,046,632 | 1,860 | 1,935 |
| 11 | Life As We Know It | Warner Bros. | 3,070,000 | 48,510,073 | 1,950 | 1,574 |
| 12 | Conviction | Fox Searchlight | 1,555,000 | 4,530,989 | 672 | 2,313 |
