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“Hunger Games” towered over new entries “Wrath of the Titans” and “Mirror Mirror” in its second weekend, grossing $61.1 million and pushing its domestic cume to $251 million. Wrath of the Titans took second place grossing $34.2 million, compared to the $61.2 opening of Clash of the Titans two years ago.
The Top-12 grossing motion pictures for the weekend, per data collected as of Sunday, April 1, 2012, is as follows:
| Rank | Film Name | Distributor Name | Weekend Revenue | Cume Revenue | Locs | Loc Avg |
| 1 | Hunger Games, The | Lionsgate | 61,100,000 | 251,032,838 | 4,137 | 14,769 |
| 2 | Wrath Of The Titans | Warner Bros. | 34,200,000 | 34,200,000 | 3,545 | 9,647 |
| 3 | Mirror Mirror | Relativity Media | 19,000,000 | 19,000,000 | 3,603 | 5,273 |
| 4 | 21 Jump Street | Sony | 15,000,000 | 93,052,624 | 3,148 | 4,764 |
| 5 | Dr. Seuss’ The Lorax | Universal | 8,013,120 | 189,560,920 | 3,264 | 2,455 |
| 6 | John Carter | Disney | 2,005,000 | 66,210,000 | 2,397 | 836 |
| 7 | Salmon Fishing in the Yemen | CBS Films | 1,274,000 | 3,170,979 | 483 | 2,637 |
| 8 | Act Of Valor | Relativity Media | 1,006,000 | 67,749,494 | 1,239 | 811 |
| 9 | Thousand Words, A | Paramount | 915,000 | 16,520,481 | 1,007 | 908 |
| 10 | Journey 2: The Mysterious Island | Warner Bros. | 835,000 | 98,480,207 | 908 | 919 |
| 11 | Project X | Warner Bros. | 825,000 | 53,371,776 | 903 | 913 |
| 12 | October Baby | IDP/Samuel Goldwyn Films | 778,642 | 3,101,393 | 387 | 2,011 |
